From April 12th to 13th, the 2024 Second Synthetic Biology Industry Expo (SBC2024), guided by the Nanjing Jiangbei New Area Life and Health Industry Development Management Office and the Chinese Society for Microbiology, and co-hosted by East China University of Science and Technology, Bio-Insight, BioValley, etc., was successfully held at the Nanjing Yangtze River International Conference Center. With the theme of "Constructing to Understand, Constructing to Apply", the conference gathered 6 academicians, more than 100 synthetic biology experts and over 3,000 industry peers to discuss the new blueprint for the future of synthetic biology. TIANS, as an engineering design group empowering the industrialization of new technologies, made a grand appearance with its synthetic biology industrialization T-EPC full-process services.

"Ju" (Joint) Efforts to Voice, Expounding the Way of Synthesis

On April 13th, at the special forum on fermentation technology, Li Xiangke, Chief Engineer of TIANS Group's Pharmaceutical and Chemical Engineering Design Company, delivered a cutting-edge sharing with the theme "From Synthetic Biology Laboratory to Green Bio-Manufacturing Factory: Making Dreams Come True".

First of all, he comprehensively introduced the future development direction of the bio-manufacturing industry focusing on the connotation, policy progress and industrialization challenges of synthetic biology, and pointed out that the key to industrialized production is to carry out reasonable calculation and design of fermenters and fermentation processes, optimize process integration and large-scale production technology in the scaling-up process, improve fermentation levels and reduce production costs. Then, he introduced the design concept of synthetic biology factories from the aspects of economy, intelligence, systematization, green environmental protection and safety, putting forward many constructive ideas for the industrialization of synthetic biology enterprises.

Li Xiangke giving a keynote speech

Taking Dreams as Horses, Making Innovations Take Root and Blossom

As a practitioner and enabler of synthetic biology industrialization, TIANS has in recent years actively relied on its understanding of cutting-edge process technologies and international design standards to create a synthetic biology industrialization T-EPC full-process service covering process technology, pilot-scale amplification, process simulation and optimization, process package compilation, engineering consulting and design, automation and informatization, intelligent equipment, as well as engineering construction and operation and maintenance. This service has been successfully applied in leading synthetic biology enterprises such as Bluepha, Huarheng Biology, Yiduoli Biology, Jinbo Biology, and Chuanning Biology.

TIANS synthetic biology industrialization T-EPC full-process service

During the conference, TIANS also reached out to the upstream and downstream of synthetic biology, showcasing its independently developed intelligent automatic cleaning machine and digital twin platform for fermentation factories.

TIANS intelligent automatic cleaning machine is a high-pressure automatic cleaning device for fermenters. It has five major measures to ensure thorough cleaning, with advantages such as high cleaning efficiency, safety and reliability. It avoids many potential safety hazards when workers enter the tank and is widely used in synthetic biology sub-sectors such as biomedicine, biological materials, medical aesthetics, new energy, and natural health products.

TIANS intelligent automatic cleaning machine

The digital twin platform for fermentation factories displayed at the conference more intuitively reflects TIANS outstanding strength in automation and informatization industry know-how. This platform integrates many practical factory functions such as fermentation factory campus planning, real-time monitoring of each floor, process flow control, energy management, report analysis, and abnormal warning. It uses 3D digital twins to intuitively monitor the operation status of fermentation factories, accurately control the process flow and production equipment, and helps fermentation enterprises achieve lean and digital production and operation.

Interface display of the digital twin platform for fermentation factories

From "Studying Things to Gain Knowledge" to "Creating Things for Application" and then to industrial transformation, synthetic biology has not only subverted the traditional acquisition mode of some plant natural products, reconstructed the traditional synthetic routes of some pharmaceutical and chemical products, but also provided cutting-edge ideas and methods for future food manufacturing, medical aesthetic health, as well as tumors and metabolic diseases. At this critical juncture of accelerating industrial transformation and changing production modes, TIANS is also digging deep into its own advantages to continuously seek directions for development and breakthroughs in the implementation of synthetic biology technologies. Industrial transformation makes innovations take root and blossom. Let us look forward to the new business forms and a brand-new future brought by synthetic biology.